INTERNATIONAL RESEARCH PROJECTS
1. Project title: Arm IschEmia Study - ARMIES
Type of project: multicenter international prospective service evaluation project
Duration: 2024 – ongoing
Organization: Vascular and Endovascular Research Network (VERN), Northern Vascular Centre, Freeman Hospital Newcastle, UK
Participants from the department: D.Casian (principal investigator), V.Culiuc (investigator)
2. Project title: Biomarkers in Prediction of Acute Mesenteric Ischemia: a prospective, multicenter study (BIPAMI)
Type of project: prospective multicenter study
Duration: 2024 – ongoing
Organization: University of Tartu; Grant PRG1255 from Estonian Research Council, investigator principal Annika Reintam Blaser
Participants from the department: D.Casian (principal investigator), Gh.Rojnoveanu (investigator), T.Malcova (investigator), E.Sor (investigator)
3. Project title: Thrombotic and Thromboembolic Complications Associated with COVID-19 Infection.
Type of project: prospective multicenter international registry
Duration: 2020 – ongoing
Organization: The Vascular Surgery COVID-19 Collaborative (VASCC) team, Dr. Max Wohlauer, University Colorado, SUA
Participants from the department: D.Casian (principal investigator), V.Culiuc (investigator)
4. Project title: Incidence, diagnosis, management and outcome of Acute MESenteric Ischemia: a prospective, multicenter observational AMESI Study
Type of project: prospective multicenter observational study
Duration: 2022 – ongoing
Organization: University of Tartu; Grant PRG1255 from Estonian Research Council, investigator principal Annika Reintam Blaser
Participants from the department: D.Casian (principal investigator), Gh.Rojnoveanu (investigator), T.Malcova (investigator), A.Ursu (investigator)
5. Project title: Prospective multicenter observational study evaluating acute lower limb ischemia „PROMOTE-ALI”
Type of project: prospective multicenter observational study, NCT05138679
Duration: 2022 – ongoing
Organization: European Vascular Research Collaborative (https://eurovascresearch.com/)
Participants from the department: D.Casian (investigator), A.Predenciuc (investigator)
6. Project title: Efficacy and safety of D-PLEX administered concomitantly with the standard of care, in prevention of post abdominal surgery incisional infection
Type of project: Phase lll, prospective, multinational, multicenter, randomized, controlled, two-arm, double blind study
Duration: 2021-2022
Organization: PolyPid Ltd, Israel
Participants from the department: E.Guțu (principal investigator), M.Sochirca (investigator)
7. Project title: Ţesut tumoral şi ţesut normal adiacent tumorii / pacienţi cu multiple tipuri de cancer
Type of project: studiu noninterventional multicentric CPTAC Phase III (Clinical Proteomics Tumor Analysis Consortium), FRT 18101
Duration: 2019 – ongoing
Organization: Fidelis Research, Romania
Participants from the department: E.Guțu (investigator)
8. Project title: National Protocol on Acute Calculous Cholecystitis in Adult
Type of project: “Quality and Efficiency of Health Services in Moldova”
Duration: 2017
Organization: GFA Consulting Group GmbH, Germany
Participants from the department: E.Guţu (short-term expert)
9. Project title: – The effect of intra-anal Nifedipine, used as add-on to conservative therapy, on pain in patients with anal fissure.
Type of project: randomized double-blinded study, protocol RDD 110
Duration: 2016-2017
Organization: RDD Pharma Ltd, Israel
Participants from the department: E.Guțu (principal investigator), M.Sochirca (investigator), S.Dovbîş (investigator)
10. Project title: Treatment of an acute deep vein thrombosis (DVT) with either rivaroxaban or current standard of care therapy „XALIA”
Type of project: prospective multicenter observational cohort study, NCT01619007
Duration: 2012 – 2015
Organization: Global Medical Affairs Therapeutic Area Head, Bayer HealthCare AG
Participants from the department: E.Guțu (principal investigator), D.Casian (investigator), V.Culiuc (investigator), M.Sochirca (investigator)
11. Project title: International Delphi-based consensus on management strategy for patients with chronic venous disease
Type of project: Delphi-based consensus
Duration: 2015
Organization: S.K. van der Velden, R. van den Bos, O. Pichot, T. Nijsten, M. De Maeseneer (Netherlands, France)
Participants from the department: D.Casian (member of expert group)
12. Project title: Delafloxacin vs vancomycin and aztreonam for the treatment of acute bacterial skin and skin structure infections
Type of project: multicenter randomized double-blind active controlled study, NCT 01984684
Duration: 2014 – 2016
Organization: Cubist Pharmaceuticals LLC
Participants from the department: E.Guțu (principal investigator), D.Casian (investigator), V.Culiuc (investigator), M.Sochirca (investigator)
13. Project title: Study comparing the safety and efficacy of intravenous cxa-201 and intravenous meropenem in complicated intraabdominal infections
Type of project: multicenter double-blind randomized study, NCT 01445678
Duration: 2011 – 2013
Organization: Cubist Pharmaceuticals LLC
Participants from the department: E.Guțu (principal investigator), D.Casian (investigator)